SGLT2 Inhibitors: A Noval Therapuetic Agent in the Treatment of Diabetic Kidney Disease
نویسندگان
چکیده
منابع مشابه
SGLT2 Inhibitors and the Diabetic Kidney.
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression. Sodium-glucose cotransporter 2 (SGLT2) inhibitors, the most recent glucose-lowering oral agents, may have the potential to exert nephroprotectio...
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nents, can lead to de novo ESRD in subjects without identifiable ESRD risks. These data also increase the urgency to identify kidney toxic dietary components and if these components can promote ESRD even in subjects who have no identifiable risk factors. Diet remains a relatively underused component of the clinician’s armamentarium in the fight to prevent patients with CKD progressing to ESRD a...
متن کاملCorrection to: SGLT2 inhibitors: a novel choice for the combination therapy in diabetic kidney disease
Following publication of the original article [1] the authors reported that the first affiliation ("Medical Center of the Graduate School, Nanchang University, China") had been added in error, and that the correct author information is as given in this erratum.
متن کاملSGLT2 inhibitors: a novel choice for the combination therapy in diabetic kidney disease
Diabetic kidney disease (DKD) is the most common cause of end stage renal disease. The comprehensive management of DKD depends on combined target-therapies for hyperglycemia, hypertension, albuminuria, and hyperlipaemia, etc. Sodium–glucose co-transporter 2 (SGLT2) inhibitors, the most recently developed oral hypoglycemic agents acted on renal proximal tubules, suppress glucose reabsorption and...
متن کاملA Potential Treatment Strategy for the Treatment of Diabetic Kidney Disease in Streptozotocin-induced Diabetic Rats: Leptadenia hastata Extract
Background: Kidney disorders are serious outcomes of diabetes, resulting in renal ailments. This study seeks to provide an alternative treatment for the disorder through the use of medicinal plants that offer renal protection and ameliorate the deleterious effect of diabetes. Methods: Thirty rats were divided into six groups of five and hyperglycemia was induced by intraperitoneal injection ...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2020
ISSN: 2250-1177
DOI: 10.22270/jddt.v10i6.4532